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dc.contributor.authorFoltyn, Jan
dc.contributor.authorProto, Antonino
dc.contributor.authorOczka, David
dc.contributor.authorHalfar, Radek
dc.contributor.authorKlinkovský, Tomáš
dc.contributor.authorŠkoloudík, Lukáš
dc.contributor.authorČerný, Michal
dc.contributor.authorChrobok, Viktor
dc.contributor.authorRyška, Aleš
dc.contributor.authorRadochová, Věra
dc.contributor.authorLitschmannová, Martina
dc.contributor.authorPenhaker, Marek
dc.contributor.authorMejzlík, Jan
dc.date.accessioned2019-09-09T06:29:46Z
dc.date.available2019-09-09T06:29:46Z
dc.date.issued2019
dc.identifier.citationScientific Reports. 2019, vol. 9, art. no. 9837.cs
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/10084/138493
dc.description.abstractThe paper examines the development and testing of an electro-pneumatic device for wound healing therapy after surgery in the neck area. The device generates air pressure values in a miniaturized cuff using electronic circuitry to drive an electro-valve and air compressor. The device works in two distinct modes: continuous pressure mode and pulsating pressure mode. The pressure value setting can vary from 3 to 11 mmHg, and the pulsating pressure mode's operating frequency range is approximately 0.1 to 0.3 Hz. Laboratory measurements were conducted to evaluate the device's correct functioning in both continuous and pulsating pressure modes. A four-day prospective study with animals (n = 10) was also conducted to evaluate neck wound healing therapy using the electro-pneumatic device. Out of the twelve histological parameters analysed to reveal the differences between the experimental and control wounds, only one demonstrated a significant difference. Out of the ten animals treated with the device, three showed a significant difference in terms of benefit after therapy. We can therefore conclude that the device potentially improves the wound healing process in the neck area if the pre-set air pressure value does not exceed 8 mmHg.cs
dc.language.isoencs
dc.publisherSpringer Naturecs
dc.relation.ispartofseriesScientific Reportscs
dc.relation.urihttp://doi.org/10.1038/s41598-019-46397-0cs
dc.rightsCopyright © 2019, Springer Naturecs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.titleEvaluation of an electro-pneumatic device for artificial capillary pulse generation used in a prospective study in animals for surgical neck wound healingcs
dc.typearticlecs
dc.identifier.doi10.1038/s41598-019-46397-0
dc.rights.accessopenAccesscs
dc.type.versionpublishedVersioncs
dc.type.statusPeer-reviewedcs
dc.description.sourceWeb of Sciencecs
dc.description.volume9cs
dc.description.firstpageart. no. 9837cs
dc.identifier.wos000474335800034


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Copyright © 2019, Springer Nature
Except where otherwise noted, this item's license is described as Copyright © 2019, Springer Nature